Und wieder eine neue Lieferung von DocGreys ScienceNews (von mir mal wieder um Ewigkeiten verschleppt)
Link(s) auf Wunsch der verlinkten Seite entfernt.
31 Oktober 2007
Science News 39/07
Einwurf
Nachdem ich wieder etwas ruhe habe und Doc Grey aus dem Urlaub ist, kommen mal wieder die Science News
Einwurf Ende
Researchers Discover Three New Genes that Cause Lung Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300006
TTF1, NKX2-8, and PAX9 on Chromosome 14 mutated in 20% of lung cancers
Scientists Discover microRNA Markers for Testicular Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34500001
Scientists at the Erasmus MC-University Medical Center in Rotterdam, The Netherlands and
Applied Biosystems an Applera Corporation business, have made significant advances in
testicular cancer research by identifying and analyzing a set of specific microRNA
molecular markers that are involved in the development of testicular tumors.
MIT Works Toward Novel Therapeutic Device
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34700004
Capturing of circulating cells out of the blood stream using cell rolling signal mechanism
PEG-coated glass slides doted with P-selectin.
Paving the Way for Future Pan-European Clinical Trials
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=34300012
European Medical Research Council (EMRC): “Pan-European collaboration is important for
many clinical trials and essential for trials that are investigating treatments for rare
diseases” EUROCORES, EURAMOS, PROFIDYS
Treatment Blocks Pain without Disrupting other Functions
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34200002
A combination of two drugs (capsaicin; QX-314)can selectively block pain-sensing neurons
in rats without impairing movement or other sensations such as touch
Potential Treatment for Huntington’s Disease
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300005
A small molecule drug called C2-8 appears to delay the loss of motor control and reduce
neurological damage in a mouse model
Engineers Study Brain Folding in Higher Mammals
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34200003
common ground between the shaping of the brain and the heart during embryonic development.
One Shot of Gene Therapy Spreads Through Brain in Animal Study
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300011
By targeting a site (ventral tegmental area ) in a mouse brain well connected to other
areas, researchers successfully delivered a beneficial gene to the entire brain
Drug Cocktail Stops Brain Damage Caused by HIV
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300007
Highly Active Anti-Retroviral Therapy (HAART)
Epstein-Barr: A Virtual Look at a Vexing Virus
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34700001
PathSim is an agent-based computer program
Antibody Leads to Repair of Myelin Sheath in Lab Study of Multiple Sclerosis and Related
Disorders
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300008
Body-mind Meditation Boosts Performance, Reduces Stress
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300010
Nature Leads the way for the Next Generation of Paints, Cosmetics and Holograms
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34200001
An extremely effective way of growing diatoms in controlled laboratory conditions was
found
Appendix Isn’t Useless After All
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34300004
It’s a safe house for bacteria
Statement by Cold Spring Harbor Laboratory Regarding James D. Watson
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=34600001
Earlier this evening, the Cold Spring Harbor Laboratory Board of Trustees decided to
suspend the administrative responsibilities of Chancellor James D. Watson, Ph.D., pending
further deliberation by the Board. This action follows the Board’s public statement
yesterday disagreeing with the comments attributed to Dr. Watson in the October 14, 2007
edition of The Sunday Times U.K.
21 September 2007
Science News 35/07
Natural Insecticide Recreated in the Lab
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33100002
synthesis of azadirachtin
Noninvasive Diagnostic Tool for Brain diseases
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33100001
Highly accurate diagnosis of brain diseases by magnetoencephalography
Isolation of a New Gene Family Essential for Early Development
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33100004
UTX-JMJD3
Clue to Mechanisms of Gene Signaling and Regulation
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33100003
Role of a repeat pattern (periodicity) of 8 to 10 base pairs between two CG dinucleotides
in the imprinting of mouse genes.
Viagra Increases Release of Key Reproductive Hormone
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33100006
Increaaed oxytocin release by phosphodiesterase type 5 inhibition
A Gene for Metastasis
Scientists reveal the actions of a key player in colorectal cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33200003
L1-CAM is only expressed on certain cells located at the invasive front of the tumor
tissue, hinting that it could be an important player in liver metastasis.
Bits of ‚Junk‘ RNA Aid Master Tumor-suppressor Gene
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=33100005
miRNA34 family and p53. „We found that expression of two of the miRNA34 genes was lost in
almost two-thirds of lung adenocarcinomas”.
Study Questions FDA Genetic-screening Guidelines for Cancer Drug
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=33200002
irinotecan intolerance testing for UGT1A1 polymorphism is only necessary in high and
medium dose treatments
27 August 2007
Science News 33/07
Einwurf
Und um Aufzuholen, gleich die Nächste hinterher
Einwurf Ende
Biofuel Economics
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=32800006
Production costs of advanced biofuels is similar to grain-ethanol
read more »
8 August 2007
Science News 31/07
Und Doc Grey hat wieder Neuigkeiten gesammelt:
Genomics Study Provides Insight into the Evolution of Unique Human Traits
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32100008
Comparing the genomes from humans to those of nine other primate species by CGH: chimpanzee, gorilla, bonobo, orangutan, gibbon, macaque, baboon,
marmoset, and lemur. copy number expansion of a gene called AQP7 could explain why humans have evolved the capacity for endurance running.
Gene copy number differences found with potential association with cognition, reproduction, immune function, and susceptibility to genetic
disease.
A Unique, Photosynthesizing Life-Form
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32100004
Two Bacteria Better Than One in Cellulose-fed Fuel Cell
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32100001
U-M Researchers Identify Gene Involved in Breast Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32000005
FOXP3
Gold Nanoparticles May Pan Out as Tool for Cancer Diagnosis
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32100007
Gold-Nanorods conjugated AB with specific plasmon detection methods can detect cancer stem cells out of blood samples. Combined detection of up
to 15 markers in the same assay possible at 1/3 of the cost of flow cytometry. Possible application in breast cancer diagnosis.
Living Virus in Novel Phase II Study for Sarcoma
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=32000001
Reolysin
New Target for HIV/AIDS Drugs and Vaccines
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32000007
A ‚Dimmer Switch‘ to Regulate Gene Expression in Mammal Cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32000009
MicroRNA Works with Ago2 Protein to Regulate Blood Cell Development
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32000008
29 Juli 2007
Science News 29/07
Einwurf
Ok, ok, ich bin wieder vieeeel zu spät mit den Science News von Doc Grey, verzeiht mir bitte.
Einwurf Ende
How HIV Interferes with Infected Cell Division
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600006
Vpr stops infected CD4+T cells from dividing. Also interacting with Upiquitination machinery by the DDB1-CUL4-VprBP complex
Cells Take Risks with their Identities
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600003
many human genes hover between ?on? and ?off? in any given cell.
Phenomenon of unfinished transcription. About one-third of our genes, including all the regulators of cell identity, fall into this class
Unraveling the Physics of DNA’s Double Helix
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600005
Next Step in Understanding Potential Target for Ovarian Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31700003
km23-Mutation in 43% of ovarian cancers found. Role in microtubuli transport of TGF signalling proteins.
Universal Flu Vaccine Being Tested on Humans
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31700002
Semiconductor Membrane Mimics Biological Behavior of Ion Channels
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600002
Plants Uptake Antibiotics
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31400006
19 Juli 2007
Science News 28/07
Life Elsewhere In Solar System Could Be Different From Life As We Know It
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200002
Soil Particles Found to Boost Prion’s Capacity to Infect
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100011
New Way to Target and Kill Antibiotic-Resistant Bacteria Found
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100006
bisphosphonates (clodronate and etidronate) inhibits E.coli DNA relaxase
Novel Genetics Research Advances Possibility Of HIV Vaccine
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200006
HLA Class 1 variations and therapy response
DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC(TM)
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31100017
Increase in Prescription Drug Cost Sharing Associated With Lower Rates of Drug Treatment, Adherence
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31000011
Pumpkin: A Fairytale End To Insulin Injections?
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200004
pumpkin extracts boost levels of beta-cells
Way to Shrink, Grow Fat Is Found
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31000002
Chronic stress and high-fat diet leads to obesity
Research Suggests Fitness May Reduce Inflammation
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100018
read more »
16 Juli 2007
Science News 27/07
Einwurf
Und wieder habe ich die SN eine Woche zu spät eingestellt. Irgendwann sollte ich mal nachsehen, ob in den News was gegen Alzheimer steht. Dank wie immer an Doc Grey!
Einwurf Ende
A Nanoscale Injector for Biological Cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600019
carbon nanotube „nanoinjector“ can introduce protein-coated quantum dots into living human cells
Bright Future for Nano-sized Light Source
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600018
first electrode-free, continuously tunable coherent visible light source on the base of potassium niobate nanowires. Also compatible with
physiological environments.
Translating Form Into Function
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30800004
first success of “decrypting” an enzyme’s function from its structure
Discovery Could Help Bring Down Price Of DNA Sequencing
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30800002
Nanopore sequencing
Scientists Discover How Stress Causes Obesity And Remove Fat Using Simple Injections
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30800005
neuropeptide Y2 receptor blocker
Probiotic Drinks Can Help Reduce Diarrhoea Associated with Antibiotics
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600015
Exercise Stimulates The Formation Of New Brain Cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600005
Adding Folic Acid To Bread Could Help In The Fight Against Depression
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500022
read more »
28 Juni 2007
Science News 25/07
Einwurf
Ich habe beschlossen die Nummerierung zu übernehmen. Verbessert die Übersicht doch ein wenig denke ich mal.
Einwurf Ende
New Applied Biosystems Software Accelerates the Identification of
Genetic Variants Used in Biomedical Research
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=29900010
Variant Reporter(TM)
Judge Blocks Generic Plavix Sale
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100050
Sleep-related Breathing Disorder Common Among Aggressive, Bullying
Schoolchildren
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=29900005
Men Suffer From Phantom Pregnancy
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100035
On The Brink Of Artificial Life
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100020
J. Craig Venter believes he is within weeks or months of creating the
world’s first free-living artificial organism in his laboratory.
Synthetic biology: Genetically engineered organisms for coal or oil
refinery, Hydrogen, ethanol or drug production.
Bacteria Ferry Nanoparticles Into Cells For Early Diagnosis, Treatment
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100007
DNA-tagged nanoparticles located at bacteria surfaces as transfection
reagent.
Encyclopedia Of DNA: New Findings Challenge Established Views On Human
Genome
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100013
ENCODE:
· Identification of numerous previously unrecognized start sites for
DNA transcription.
· Evidence that, contrary to traditional views, regulatory sequences
are just as likely to be located downstream of a transcription start
site on a DNA strand as upstream.
· Identification of specific signatures of change in histones, which
are the proteins that organize DNA, and correlation of these signatures
with different genomic functions.
· Deeper understanding of how DNA replication is coordinated by
modifications in histones.
Mutating The Entire Genome
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100032
mutating large, non-gene stretches of DNA
Clocking In And Out Of Gene Expression
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100025
A chemical signal acts as time clock in the expression of genes
controlled by a master gene called a coactivator. Using steroid receptor
coactivator-3 (SRC-3), it was demonstrated that activation requires
addition of a phosphate molecule to the protein at one spot and addition
of an ubiquitin molecule at another point. Each time the message of the
gene is transcribed into a protein, another ubiquitin molecule is
chained on. Five ubiquitins in the chain and the protein is
automatically destroyed.
In Nature, Proteins Sweep Up Nanoparticles
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100019
proteins that sweep up metal nanoparticles into immobile clumps
Potent Possibilities For Parasite Attack
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100030
Leishmaniasis treatment
Colon Cancer Proteins Show Promise For Blood Test
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100018
CCSA-3 and CCSA-4; 100% sensitivity for cancer detection
In ‚Spontaneous‘ Liver Cancer, Researcher Sees a Cure
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30200001
Loss of one copy of the embryonic liver fodrin gene cause spontaneous
Liver cancer
Antitumor Compound Blocks Heat Shock Protein
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100010
Deguelin
First Compact Proton Therapy Machine For Cancer Treatment Enters Development
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100044
Vegenics Licenses From CoGenesys Antibodies Against VEGF-C for
Applications Including Oncology
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100038
Prolexys Pharmaceuticals and Columbia University Researchers Publish
Study on Anti-Tumor Properties of a Selective Small Molecule Anti-Tumor
Agent With Novel Mechanism of Action
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100004
erastin binds to mitochondrial voltage- dependent anion channels (VDACs)
Related drug candidate: PRLX 93936
Allos Therapeutics, Inc. Scraps Brain Cancer Drug After Trial Failure
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100053
CSHL Scientists Successfully Target Tumor Microenvironment To Stop
Cancer Growth
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100016
Deletion of endothelial progenitor cells, which play a role in early
tumor vascularisation.
Cancer Stem Cells Similar To Normal Stem Cells Can Thwart Anti-cancer Agents
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100028
How Tumor Cells Home In On The Lymphatic System
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100011
Tumor cells follow lymph vessel signalling molecule during fluid flow
from umor to vessel. Possible new target for Anti-Lymphnodemetastatis drugs.
Virologists Show How „Memory“ T Cells Curb the Spread of Viruses
Throughout the Body
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100046
Lymph nodes as check points preventing virus spread
ThermoGenesis and University of California, Davis Stem Cell Program
Collaborate to Develop Stem Cell Treatments for Major Diseases
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100052
Rising Skin Cancer Rates Are More Likely To Affect Wealthy People, Says
12-year Review
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=29900013
Scientists De-Code RNA Mystery, Will Help Aim Drug Therapies
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=29900003
Nanoparticle Offers Promise For Treating Glaucoma
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100047
cerium oxide nanoparticle plus hCAII-Blocker
Scientists Culture Blood-forming Stem Cells From Human Fat Tissue
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100027
Mucosal-Surface Immune Function Discoveries Could Boost Vaccine Research
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100014
APRIL+IgA2
Ralphs Piratenblog 