Science News 28/07

Life Elsewhere In Solar System Could Be Different From Life As We Know It
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200002

Soil Particles Found to Boost Prion’s Capacity to Infect
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100011

New Way to Target and Kill Antibiotic-Resistant Bacteria Found
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100006
bisphosphonates (clodronate and etidronate) inhibits E.coli DNA relaxase

Novel Genetics Research Advances Possibility Of HIV Vaccine
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200006
HLA Class 1 variations and therapy response

DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC(TM)
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31100017

Increase in Prescription Drug Cost Sharing Associated With Lower Rates of Drug Treatment, Adherence
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31000011

Pumpkin: A Fairytale End To Insulin Injections?
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200004
pumpkin extracts boost levels of beta-cells

Way to Shrink, Grow Fat Is Found
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31000002
Chronic stress and high-fat diet leads to obesity

Research Suggests Fitness May Reduce Inflammation
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100018

Chronically Sleep Deprived? You Can’t Make Up For Lost Sleep
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100015

Research team discovers gallstone gene
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31400004
ABCG8-gene

Engineered Blood Vessels Function like Native Tissue
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100004
bone marrow is an excellent source of adult stem cells containing smooth muscle and endothelial cells.

New ‚Asthma Gene‘ Could Lead to New Therapies
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31000005
ORMDL3

MicroRNAs May Explain Psoriasis
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31400005

Penn researchers show how microRNAs control protein synthesis
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31300004

NIEHS Researchers Identify Enzyme Critical in DNA Replication
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100010
DNA Polymerase Epsilon has a primary role in replicating the leading strand of DNA and was found to be a key determinant of genome stability.

Antibody retards growth and induces death in liver cancer cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31400001
Anti-PDGFRá-AB

New use for a cell toxin found to inhibit survival proteins in cancer cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31400002
2-Methoxy antimycin inhibits Bcl2 and Bcl-xL

Major Advance in Search for Genes Associated with Colon Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100007
C allele of rs10505477 and 8q24 ,also breast and prostate cancer

Hormone Inhibitor Promising For Hard-to-treat Prostate Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200005
abiraterone, a CYP450c17 Inhibitor, reduces levels of prostate specific antigen also in hormone refractory patients

Skin Rash Actually Signifies Better Outcomes for Pancreatic and Lung Cancer Patients
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30900008
Skin rash after Tarceva treatment is associated with better survival

Discovery about Obesity Drug Helping Scientists Develop New Cancer Treatments
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31100005
orlistat (Xenical® or Alli®) inhibits in several tumor types (breast, colon, ovarian, liver, lung and brain) highly expressed fatty acid synthase and causes apoptosis.

Is milk thistle effective in cancer treatment?
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31300002

Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31000009
miR-34a

Northwest BioTherapeutics Gains Cancer Vaccine Approval
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31300005
DCVax-Brain

World’s First Therapeutic Vaccine for Brain Cancer Commercially Available to Patients in Switzerland
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31200008

Geron Initiates Clinical Trial of Telomerase Inhibitor Drug in Combination With Paclitaxel and Carboplatin in Patients With Non-Small
Cell Lung Cancer
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31200007
GRN163L

YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds To The EGF Receptor And Potentiates Radiotherapy
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31200012

Roche and Alnylam Form Major Alliance on RNAi Therapeutics
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31200011

Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European
Society for Medical Oncology
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31200010
isophosphoramide mustard – IPM

Genaera Discontinues LOMUCIN(TM) in Cystic Fibrosis and Squalamine in Prostate Cancer Studies
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=31000010

Children’s Scientists Discover Fundamental Protein Instrumental To Brain Development And Repair
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31200003Over-expression (through genetic manipulation) of epidermal growth factor receptor (EGFR) protein promotes both myelination and remyelination (creation and repair of white matter).