Archiv für ‘entwicklung’

24 September 2007

100 € Laptop für jeden

Bei Golem und Heise ist zu lesen, dass man unter http://www.xogiving.org/ (momentan leider wegen Überlastung down) ab 12.11.2007 einen der Laptop kaufen kann. Leider(?) nicht für die angekündigten (und mehr als nur einmal revidierten) 100$ sondern für voraussichtlich 399$. Damit kauf man jedoch gleich einen 2. Laptop, der als Spende weitergereicht wird.

Für jeden, der nicht viel mehr als eine tragbare Schreibmaschine baucht, wäre dies vielleicht eine gute Idee um etwas gutes zu tun. (und wer sich eh n Laptop für 1500€ kauft, der kann ja auch so die 200€ spenden, da kommt es ja nicht mehr darauf an, oder? ;)

Siehe auch bei Wikipedia.

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27 August 2007

Science News 32/07

Einwurf
Mit ziemlicher Verspätung (von mir!) kommen jetzt mal wieder einige von Doc Greys Science News.
Einwurf Ende

E. coli Bacteria Linked to Crohn’s Disease
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32500001

Caffeine may Protect Memory in Women
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32400007

Metal Ions Linked to Neurodegenerative Disease
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32400008
Role of Copper in amyloid cytotoxicity

Discredited Korean Embryonic Stem Cells’ True Origins Revealed
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32000006

Anthrax Bacterium’s Deadly Secrets Probed
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32400006

Why Red Beans and Rice can be Nauseating
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32200006
Lectins inhibit selfrepair of gastrointestinal endothelium cells

A Sensory Organ, not the Brain, Differentiates Male/Female Behavior in
Some Mammals
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32400002

Defects in Critical Gene Lead to Accelerated Lung Tumor Growth
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32400001
LKB1

BioServe and Phenomenome Discoveries Develop Novel Diagnostic Test for
Colorectal Cancer
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=32400004
Serum Metabolic marker. 75% sens. 90% spec.

Gene Fusion Subtypes In Prostate Carcinoma Have Clinical Implications
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32300001
Oncomine gene expression Database

A Family of ‘On Switches’ that Cause Prostate Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32200007
TMPRSS2
and 5 other genes, which fuses with either ERG or ETV1


New Sampling Technique Allows for Earlier Diagnosis of Pancreatic Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32200002
A new optical technology, coupled with routine endoscopy, may enable
doctors to detect the subtle tell-tale traces of early pancreatic
cancer. Four-dimensional elastic light scattering fingerprinting
(4D-ELF) and low-coherence enhanced backscattering spectroscopy (LEBS).
Different light refraction by nanoscale structures in healthy and cancer
tissue.

COX-2 Inhibitors Delay Pancreatic Cancer Precursors in Mice
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=32200001
Nimesulide

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10 August 2007

Angepasste Technik, oder Steckdosen gibt es nicht in jedem Dorf

Danke an das MAKE Blog, dadurch bin ich gerade über William Kamkwamba Windmühlenblog gestolpert.

Ich bin auch, die von MAKE, einfach mal so frech und kopiere einen Teil aus seinem ersten Blogeintrag, ich denke, es ist eine gute Zusammenfassung, um was es eigentlich geht.

Our family is poor like many families in Malawi and Africa, and as a result, we have no electricity in our village or my home. For many years we had only paraffin candles to light my home at night. They are expensive, smoky, smelly and have to be purchased about 8 km from home.

During that time I decided to try to get as much education as possible by reading as many books as I could find. An organization called the Malawian Teacher Training Activity (MTTA), a project of USAID contributed a large quantity of books to the primary school library near my home. I read many of them. One of the books I read was called Using Energy, a primary school textbook about how energy is made. Inside the book there were plans for a windmill. I decided to build a windmill to provide power for my family.

Es scheint, dass Bücher wirklich die bessere Entwicklungshilfe sind.

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9 August 2007

Wikipedia: Automatisiertes Vertrauen

Beim UC Santa Cruz gibt es gerade ein Forschungsprojekt, welches eine Analyse erstellen will, wie sehr einzelne Bereiche eines Textes in der Wikipedia vertrauenswürdig sind. Dazu werden Textbereiche, die von “fragwürdigen” Editoren stammen farblich unterlegt. Je mehr Farbe, desto vorsichtiger sollte man mit den Text umgehen.

Natürlich handelt es sich dabei auch nur um ein Hilfsmittel. Wenn ein Dr. Dr. Dr. Müller als erstes einen neuen Artikel einstellt und er vorher noch nie was in der Wikipedia gemacht hat, wird der Artikel komplett eingefärbt sein, egal wie gut der Artikel ist. Solche Fälle sind inzwischen in den größeren Sprachversionen (Englisch, Deutsch, Fanzösisch, Polnisch) eher eine Seltenheit.

Im Moment gibt es leider nur ein paar hundert Seiten, die bearbeitet wurden und ein Einbau in die Wikipedia selbst ist wegen der wahrscheinlich ziemlich hohen Last für die Rechner doch unwahrscheinlich. Aber vielleicht wird man ja bald zumindest als Administrator so ein Tool zur Verfügung haben, wenn die lange angekündigte stabile Versionen mal endlich da sind.

Zufallsseiten mit den Markierungen (en)

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2 August 2007

Science News 30/07

A Blueprint for ‘Smart’ Health Care
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=31900004

Novel Hydrogels for Repairing, Regenerating Human Tissue
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31700007

Genomic Analysis Uncovers New Targets for HIV Vaccine
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31700014
3 Polymorphisms responsibe for delayed progression. Possible role for HLA-C as vaccine target.

29 Juli 2007

Science News 29/07

Einwurf

Ok, ok, ich bin wieder vieeeel zu spät mit den Science News von Doc Grey, verzeiht mir bitte.

Einwurf Ende

How HIV Interferes with Infected Cell Division
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600006
Vpr stops infected CD4+T cells from dividing. Also interacting with Upiquitination machinery by the DDB1-CUL4-VprBP complex

Cells Take Risks with their Identities
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600003
many human genes hover between ?on? and ?off? in any given cell.
Phenomenon of unfinished transcription. About one-third of our genes, including all the regulators of cell identity, fall into this class

Unraveling the Physics of DNA’s Double Helix
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600005

Next Step in Understanding Potential Target for Ovarian Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31700003
km23-Mutation
in 43% of ovarian cancers found. Role in microtubuli transport of TGF signalling proteins.

Universal Flu Vaccine Being Tested on Humans
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31700002

Semiconductor Membrane Mimics Biological Behavior of Ion Channels
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31600002

Plants Uptake Antibiotics
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=31400006

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16 Juli 2007

Bericht über den Loremo

Bei Telopolis gibt es einen Artikel über den Loremo, der die frage stellt, ob mal mehr als nur ein Prototyp rauskommen wird.

Ich hoffe ja immer noch, dass dieses (noch Münchner?) Auto erscheinen wird, aber wie auch in dem Artikel gezeigt und schon oft genug selbst erlebt….Autos, die in 10 Jahren kommen sollen, sind nach 10 Jahren immer noch 10 Jahre entfernt.

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16 Juli 2007

Science News 27/07

Einwurf

Und wieder habe ich die SN eine Woche zu spät eingestellt. Irgendwann sollte ich mal nachsehen, ob in den News was gegen Alzheimer steht. Dank wie immer an Doc Grey!

Einwurf Ende

A Nanoscale Injector for Biological Cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600019
carbon nanotube “nanoinjector” can introduce protein-coated quantum dots into living human cells

Bright Future for Nano-sized Light Source
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600018
first electrode-free, continuously tunable coherent visible light source on the base of potassium niobate nanowires. Also compatible with
physiological environments.

Translating Form Into Function
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30800004
first success of “decrypting” an enzyme’s function from its structure

Discovery Could Help Bring Down Price Of DNA Sequencing
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30800002
Nanopore sequencing

Scientists Discover How Stress Causes Obesity And Remove Fat Using Simple Injections
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30800005
neuropeptide Y2 receptor blocker

Probiotic Drinks Can Help Reduce Diarrhoea Associated with Antibiotics
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600015

Exercise Stimulates The Formation Of New Brain Cells
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30600005

Adding Folic Acid To Bread Could Help In The Fight Against Depression
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500022

5 Juli 2007

Science News 26/07

Nanoparticles Hitchhike On Red Blood Cells: A Potential New Method For Drug Delivery
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500019
Enhanced drug stability

The Role of Environmental Factors in the Development of Parkinson’s Disease
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500018
Iron, paraquat and Anti-Oxidants

Gene Variant Increases Risk For Acoholism Following Childhood Abuse
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500006
MAOA

Computerized Doctors’ Orders Reduce Medication Errors
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500021

Donated Embryos Could Result in More Than 2,000 Embryonic Stem Cell Lines
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30400006

Five Genetic Themes Key To Keeping Stem Cells In A Primitive, Flexible State Have Been Identified
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30400004
Oct4-and
other regulators

Male Twins Can Reduce Their Sister’s Fertility
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30300010

Surprising Origin Of Cell’s Internal Highways
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30300008
Centrosome and Golgi (movement related)

Researchers Develop Buckyballs to Fight Allergy
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30300007
Water soluble fullerenes with highest radical binding properties in the body.

3-D Ultrasound Scanner Provides In-depth View Of The Brain
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30400003

AAAS Comments On Stem Cell Veto And Executive Order
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30400011

Scientists Call For Global Push To Advance Research In Synthetic Biology
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500005

Demonic Possession And Mraculous Healing
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500003
Concepts of ‘Health and the Healthy Body’ in early medieval times, 400-1200AD

Omega-3s May Help Slow Prostate Cancer Growth
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30400017

New Research Project: Curing Cancer With Mathematics
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30400016
Optimisation of therapy: sequence of treatments, contribution ratio of different regimens, time intervals.

Researchers at Rice University Use Cray Supercomputer to Unlock Biomedical Mysteries and Aid Future Diagnostics
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=30500010

Scripps Research Scientists Show Protein Accelerates Breast Cancer
Progression In Animal Models
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30300006
pleiotrophin (PTN) excretions induces aggressive tumor behaviour.

Researchers Pit Novel Version Of Common Virus Against Cancer
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30300005
new oncolytic adenovirus with mutated DNA polymerase (dNTP), targeting high NTPs containing cells.

Researchers Identify Target of Angiogenesis and Tumor Inhibitor
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500016
vimentin is the binding target of withaferin-A

Oncolytics Biotech Inc. Commences Patient Enrolment in U.S. Phase II
Sarcoma Clinical Trial
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=30500024
Reolysin

TU Delft Tracks The Influence Of A Cancer Inhibitor On A Single DNA Molecule
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30500002
Topotecan interacts with TopoIB, a protein responsible for the removal of loops from DNA

Scientists Discover New Role for MicroRNAs in Stopping Tumor Cell Growth
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30300001
p53-miR-34

Coley Pharmaceutical Group Announces Pfizer Inc. Discontinuation of Clinical Trials for PF-3512676 Combined with Cytotoxic Chemotherapy in Advanced Non Small Cell Lung Cancer
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30300009

Intradigm Selects Agilent Technologies as Manufacturing Partner for Novel RNA Interference Oncology Therapeutic
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=30500009
ICS-283
: VEGF-siRNA

Kiadis Pharma Raises euro 15 million to Advance Oncology Pipeline
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=30500014
ATIR enables the use of mismatched bone-marrow donors in transplantations for terminally ill blood cancer patients

Health Canada Approves ADVR’s Application for Clinical IND
http://www.bio.com/newsfeatures/newsfeatures_industry.jhtml?cid=30500012

Althea Technologies Contracted by GeoVax to Produce a Phase 2 AIDS Vaccine
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30300002

Researchers Find New Pathway to Thwart Antibiotic Resistance
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30400007
New information about bacterial RNA Polymerase

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28 Juni 2007

Science News 25/07

Einwurf

Ich habe beschlossen die Nummerierung zu übernehmen. Verbessert die Übersicht doch ein wenig denke ich mal.

Einwurf Ende

New Applied Biosystems Software Accelerates the Identification of
Genetic Variants Used in Biomedical Research
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=29900010
Variant Reporter(TM)

Judge Blocks Generic Plavix Sale
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100050

Sleep-related Breathing Disorder Common Among Aggressive, Bullying
Schoolchildren
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=29900005

Men Suffer From Phantom Pregnancy
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100035

On The Brink Of Artificial Life
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100020
J. Craig Venter believes he is within weeks or months of creating the
world’s first free-living artificial organism in his laboratory.
Synthetic biology: Genetically engineered organisms for coal or oil
refinery, Hydrogen, ethanol or drug production.

Bacteria Ferry Nanoparticles Into Cells For Early Diagnosis, Treatment
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100007
DNA-tagged
nanoparticles located at bacteria surfaces as transfection
reagent.

Encyclopedia Of DNA: New Findings Challenge Established Views On Human
Genome
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100013
ENCODE:
· Identification of numerous previously unrecognized start sites for
DNA transcription.
· Evidence that, contrary to traditional views, regulatory sequences
are just as likely to be located downstream of a transcription start
site on a DNA strand as upstream.
· Identification of specific signatures of change in histones, which
are the proteins that organize DNA, and correlation of these signatures
with different genomic functions.
· Deeper understanding of how DNA replication is coordinated by
modifications in histones.

Mutating The Entire Genome
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100032
mutating large, non-gene stretches of DNA

Clocking In And Out Of Gene Expression
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100025
A chemical signal acts as time clock in the expression of genes
controlled by a master gene called a coactivator. Using steroid receptor
coactivator-3 (SRC-3), it was demonstrated that activation requires
addition of a phosphate molecule to the protein at one spot and addition
of an ubiquitin molecule at another point. Each time the message of the
gene is transcribed into a protein, another ubiquitin molecule is
chained on. Five ubiquitins in the chain and the protein is
automatically destroyed.

In Nature, Proteins Sweep Up Nanoparticles
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100019
proteins that sweep up metal nanoparticles into immobile clumps

Potent Possibilities For Parasite Attack
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100030
Leishmaniasis treatment

Colon Cancer Proteins Show Promise For Blood Test
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100018
CCSA-3
and CCSA-4; 100% sensitivity for cancer detection

In ‘Spontaneous’ Liver Cancer, Researcher Sees a Cure
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30200001
Loss of one copy of the embryonic liver fodrin gene cause spontaneous
Liver cancer

Antitumor Compound Blocks Heat Shock Protein
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100010
Deguelin

First Compact Proton Therapy Machine For Cancer Treatment Enters Development
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100044

Vegenics Licenses From CoGenesys Antibodies Against VEGF-C for
Applications Including Oncology
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100038

Prolexys Pharmaceuticals and Columbia University Researchers Publish
Study on Anti-Tumor Properties of a Selective Small Molecule Anti-Tumor
Agent With Novel Mechanism of Action
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100004
erastin binds to mitochondrial voltage- dependent anion channels (VDACs)
Related drug candidate: PRLX 93936

Allos Therapeutics, Inc. Scraps Brain Cancer Drug After Trial Failure
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100053

CSHL Scientists Successfully Target Tumor Microenvironment To Stop
Cancer Growth
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100016
Deletion of endothelial progenitor cells, which play a role in early
tumor vascularisation.

Cancer Stem Cells Similar To Normal Stem Cells Can Thwart Anti-cancer Agents
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100028

How Tumor Cells Home In On The Lymphatic System
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100011
Tumor cells follow lymph vessel signalling molecule during fluid flow
from umor to vessel. Possible new target for Anti-Lymphnodemetastatis drugs.

Virologists Show How “Memory” T Cells Curb the Spread of Viruses
Throughout the Body
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100046
Lymph nodes as check points preventing virus spread

ThermoGenesis and University of California, Davis Stem Cell Program
Collaborate to Develop Stem Cell Treatments for Major Diseases
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=30100052

Rising Skin Cancer Rates Are More Likely To Affect Wealthy People, Says
12-year Review
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=29900013

Scientists De-Code RNA Mystery, Will Help Aim Drug Therapies
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=29900003

Nanoparticle Offers Promise For Treating Glaucoma
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100047
cerium oxide nanoparticle plus hCAII-Blocker

Scientists Culture Blood-forming Stem Cells From Human Fat Tissue
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100027

Mucosal-Surface Immune Function Discoveries Could Boost Vaccine Research
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml?cid=30100014
APRIL+IgA2

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